From Los Banos: Travel east on Pacheco Blvd to Mercey Springs Road. Turn left on Mercey Springs Road. Continue on Mercey Springs Road for approximately 3 miles to Henry Miller Road. Turn right on Henry Miller Road and continue for approximately 7 miles to Turner Island Road (4-way stop). Turn left on Turner Island Road. After approximately 5.25 miles, turn right onto Sand Slough Road. Sand Slough Road will curve to the left and become Nickel Road. After approximately 1 mile, the road makes a sharp right and becomes Sandy Mush Road. Continue on Sandy Mush Road for approximately 3.5 miles to the refuge entrance on the right (south) side of the road.

From CA-99: Take the CA-152 west exit and travel westbound on CA-152 for approximately 15 miles. Take the CA-59 north exit toward Merced and travel north for approximately 7 miles to Sandy Mush Road. Turn left on Sandy Mush Road and travel westbound for approximately 8 miles to the refuge entrance on the left (south) side of the road.

From Interstate 5: Take the Los Banos/CA-152 east exit. Travel on CA-152 eastbound into Los Banos. Turn left on Mercey Springs Road. Continue on Mercey Springs Road for approximately 3 miles to Henry Miller Road. Turn right on Henry Miller Road and continue for approximately 7 miles to Turner Island Road (4-way stop). Turn left on Turner Island Road. After approximately 5.25 miles, turn right onto Sand Slough Road. Sand Slough Road will curve to the left and become Nickel Road. After approximately1 mile, the road makes a sharp right and becomes Sandy Mush Road. Continue on Sandy Mush Road for approximately 3.5 miles to the refuge entrance on the right (south) side of the road.