From Hwy 25: Turn east off Highway 25 onto Loakfoma Road (coming from the north turn left at the first road after entering Winston County). At the end of Loakfoma Road turn left and the Office/Visitor Center will be 6.7 miles on the left. 

From Hwy 45: Turn west off Highway 45 to Brooksville. Go through Brooksville on Lynn Creek Road and continue approximately 11 miles. The road turns right and at a four-way intersection there will be a sign for the refuge, turn right. Continue approximately three miles and turn left at paved intersection. Office/Visitor Center will be on the right .2 miles.

From Hwy 12:Look for a sign at the corner with the Hampton Inn and turn south onto Blackjack Road. Continue to the “round-a-bout” and exit to the right of the Shell Station. Continue south on Oktoc Road to the Refuge about 14 miles. Cross the Bluff Lake Levee and turn right. The Office/Visitor Center will be on your right.