From Naples Area:

Take I-75 South towards Miami. Get off at Exit 80. Turn left on State Road 29, heading North. The refuge trails will be located on the left-hand side about a half mile down the road. 

From Immokalee Area:    

Take State Road 29 South. The refuge trails will be located on the last right-hand side gate right before the on/off ramps for I-75.

Headquarters Office - TEMPORARILY CLOSED UNTIL FURTHER NOTICE

Email: floridapanther@fws.gov