Shallow wetlands rich in emergent and submerged vegetation provide an abundant food source for thousands of migrating waterfowl. Much of the 4,416-acre refuge is closed to waterfowl hunting, but the 750-acre Hanson Unit is open two days a week throughout the waterfowl season. Permits are issued via lottery, and youth hunters receive preference. Hunters are assigned one of three hunt areas on the Hanson Unit. Louisiana state regulations for the Coastal Zone are in effect.
Archery hunting for deer allows hunters access to most of the refuge, but because of large wetland expanses deer hunting can be difficult and limited to small ridge or levee areas. Feral hogs also may be taken during the archery season. Airboats and marsh buggies are not permitted on the refuge.