Fishing season is in accordance with state regulations. Available species include rainbow, cutthroat and brown trout, plus mountain whitefish. The Green River is open to fishing throughout the refuge. Half of the refuge has restricted fishing regulations that permit the use of artificial flies and lures only and limit the size and number of trout an angler may possess. The refuge's facilities include four boat ramps. Vehicle travel is restricted to designated refuge roads. The Green River is a shallow, swift river with many rocks hidden beneath the surface. It is best suited for canoes, drift boats and rafts; motors are not recommended. Personal watercraft, airboats and jet boats are prohibited.
Seedskadee National Wildlife Refuge (NWR) is well known for the fishing opportunities the Green River offers. There are not as many fish per mile as other places on the Green, but the solitude coupled with the scenery and occasional 20+ inch trout is a unique experience available on the refuge. Special fishing regulations are in effect from upstream of the Refuge boundary at the CCC County Road 8 Bridge, downstream to the confluence with the Big Sandy River - only artificial flies and lures can be used and creel limit is one trout per day over 20 inches. All other fish must be immediately released. Visit the Wyoming Game and Fish Department website for clarification or a hard copy of state regulations.