The Big Creek crayfish is a small, olive-tan crayfish that is found in only one watershed in southeast Missouri, the Upper St. Francis River watershed. The species occupies both intermittent and perennial streams and is found under small rocks and in shallow burrows in gravel. Though the Big Creek crayfish is common and abundant in many places in its range, it is being impacted by the woodland crayfish, a crayfish native to Missouri, but not to the Upper St. Francis River watershed.