Much of what is known about VI boa life history comes from studies in captivity. Life spans in captivity often exceed 20 years, but typical life spans in the wild are not known.

VI boa females breed biennially, but studies have suggested that annual breeding may occur in some conditions. Courtship behaviors and copulation occur from February through May, with a gestation period of about 4 months. VI boas give birth to live young from late August to October with litters of 2 to 10 young. Female VI boas do not lay nor incubate eggs, but rather they give birth to fully developed young. 

The VI boa occurs in subtropical dry and subtropical moist forests. Habitat needs for VI boas can be divided into those for foraging and those for resting. Some factors contributing to the quality of the habitat are tree density and connectivity, and presence of arboreal and ground-level refugia. Tree density is more important than tree species or diversity; VI boas do not appear to prefer particular tree species after accounting for availability and structure structure
Something temporarily or permanently constructed, built, or placed; and constructed of natural or manufactured parts including, but not limited to, a building, shed, cabin, porch, bridge, walkway, stair steps, sign, landing, platform, dock, rack, fence, telecommunication device, antennae, fish cleaning table, satellite dish/mount, or well head.

Learn more about structure . Connectivity is achieved in the canopy via interlocking horizontal branches between trees, which allow boas to move from tree to tree without having to descend to the ground. They seek refuge during the day in the axils of tree trunks and branches, tree holes, termite nests, or under rocks and debris. 

The VI boa is a predator that mostly preys on lizards, hunting them by sliding along tree limbs. It also feeds on rodents and young birds and small green iguanas. A constrictor snake, the VI boa wraps its body around its prey, squeezing until the prey is asphyxiated before swallowing it headfirst.

The VI boa is considered nocturnal, but some can be active during the day. The species is primarily arboreal and forages in trees at night, but it will use terrestrial refugia and disperse along the ground. Little is known about VI boa movement, the study of which is challenging because of the rarity and secrecy of the species and difficulty accessing its habitat.

The VI boa is a medium length, slender snake with an arrow-shaped head and blunt nose. The species can reach 4 feet (1.2 meters) in length, although most adults range from 2 to 3 feet (61 to 91 centimeters). 

Adults are gray-brown with dark brown blotches that are partially edged with black and feature a blue-purple iridescence on their dorsal surface; the ventral surface is creamy white or yellowish white. Neonates, on the other hand, have an almost greyish-white body color with black blotches. VI boas' eyes are considered a silvery color.