Sicyos albus, of the gourd family (Cucurbitaceae), is an annual vine up to 20 m (65 ft) long, minutely hairy, and black-spotted. Leaves are pale, broadly heart-shaped, shallowly to deeply three to five-lobed, 7 to 11 cm (2.8 to 4.3 in) long, and 9 to 12 cm (3.5 to 4.7 in) wide. Male and female flowers are borne in separate flower clusters on the same plant. Male flower clusters have main stalks 2.5 to 3.7 cm (1 to 1.5 in) long and individual flower stalks 2 to 4 mm (0.08 to 0.1 in) long. The male flowers are white, five-lobed, dotted with glands, and 2 to 2.5 mm (0.08 to 0.09 in) long. The female flower clusters have two to eight flowers, a main stalk 1 to 3.5 cm (0.4 to 1.4 in) long, and no stalks on the individual flowers. The flowers are white and four-lobed, with the lobes 1.7 to 2 mm (0.07 to 0.08 in) long. The fruit is white, fleshy, oblong, 29 to 32 mm (1.1 to 1.3 in) long, and 10 to 11 mm (about 0.4 in) wide. This species can be distinguished from its nearest relative, Sicyos cucumerinus, by its white fruit without bristles and ten or fewer female flowers per cluster.